What does the PICO framework stand for, and how is it used in formulating clinical questions?

What does the PICO framework stand for, and how is it used in formulating clinical questions?

• A. Population, Intervention, Comparison, Outcome; used to design experiments in the lab.
• B. Population, Intervention, Comparator, Outcome; used to specify a focused question for literature searching and appraisal.
• C. Probability, Intervention, Control, Outcome; used to assess statistical power.
• D. Population, Intervention, Correlate, Outcome; used to identify confounders.

Answer: (B)